Sidaguri medicinal plants, celery and tempuyung can be used as an herbal anti-gout or gout-lowering herbal formula with an inhibitory mechanism against the enzyme xanthine oxidase (XO). This enzyme is an enzyme that can catalyze oxidation of xanthine to uric acid. The discovery of anti-gout standardized extract as a phytopharmaca material was achieved through a series of studies from upstream to downstream conducted by researchers from 2003 to 2011.